Tetrahedron Letters p. 6546 - 6550 (2015)
Update date:2022-07-31
Topics:
Roberts, Lee R.
Corbett, Matthew S.
Fussell, Steven J.
Hitzel, Laure
Jessiman, Alan S.
Mason, Helen J.
Osborne, Rachel
Ralph, Michael J.
Stennett, Adam S.D.
Wheeler, Simon
Storer, R. Ian
The synthesis of a series of chiral indanes with reported α1A partial agonist activity is outlined, applying a rhodium catalysed cyclisation for template construction. This method was extended to the asymmetric synthesis of lead compound PF-037
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