Asymmetric Synthesis of the Carbapenem Antibiotic (+)-PS-5

DOI: 10.1021/jo00391a073

Source and publish data:

Journal of Organic Chemistry p. 3488 - 3489 (1987)

Update date:2022-07-31

Topics:

Authors:

Shibasaki, Masakatsu

Ishida, Yasuko

Iwasaki, Genji

Iimori, Takamasa

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00391a073

An asymmetric synthesis of (+)-PS-5 (1) has been accomplished by a route utilizing the anti-selective boron enolate-imine condensation reaction with extremely high asymmetric induction.

Full text of DOI:10.1021/jo00391a073

Products guided by the article

Product name:(2S,3R)-2-Ethyl-3-((S)-1-phenyl-ethylamino)-5-trimethylsilanyl-pent-4-ynethioic acid S-phenyl ester

Cas No:109278-33-3

R&D Labs maybe for 109278-33-3

Yingkou Sanzheng Organic Chemical Co. Ltd.

Contact:+86-417-3638818

Address:25 Gengxinli Village, Daqing Road, Yingkou, Liaoning, China
Tianjin Jiuri New Materials Co., Ltd.

Contact:+86-22-58889220

Address:C-5/6, Vison Hill, No.1 Gonghua Road, Huayuan Hi-tech Park, Tianjin, China.
Shanghai Intime pharm Co.,Ltd

Contact:86-21-58226973

Address:No 351,Guoshoujing Road, Zhangjiang Hi-tech Park, Pudong, Shanghai, China
Zhejiang Kangfeng Chemical Co.,LTD.

Contact:+86-579-86709687

Address:Xueshizhai Industrial Zone, Weishan Town,Dongyang City, Zhejiang Province ,China
Hubei Vanz Pharm Co.,Ltd

website:http://www.vanzpharm.com/en/index.html

Contact:86-27-84492310

Address:FANHU INDUSTRY PARK

Relevant to this article

Synthesis and evaluation of fluoroquinolone derivatives as substrate-based inhibitors of bacterial efflux pumps

Doi:10.1016/j.ejmech.2008.01.042
(2008)
Doi:10.1002/ardp.19592920205
(1959)
Highly regioselective tandem formal substitution and decarboxylation of 2-acyl-1-chlorocyclopropanecarboxylates with sodium sulfinates

Doi:10.1016/j.tet.2016.04.062
(2016)
Paclitaxel succinate analogs: Anionic and amide introduction as a strategy to impart blood-brain barrier permeability

Doi:10.1016/j.bmcl.2008.09.103
(2008)
Chelation-assisted, copper(II)-acetate-accelerated azide-alkyne cycloaddition

Doi:10.1021/jo101305m
(2010)
Di-, tri-, tetra-, and hexanuclear copper(ll) mono-organophosphates: Structure and nuclearity dependence on the choice of phosphorus substituents and auxiliary n-donor ligands

Doi:10.1021/ic801532y
(2009)

Article Doi