Asymmetric Synthesis of the Carbapenem Antibiotic (+)-PS-5

DOI: 10.1021/jo00391a073

Source and publish data:

Journal of Organic Chemistry p. 3488 - 3489 (1987)

Update date:2022-07-31

Topics:

Authors:

Shibasaki, Masakatsu

Ishida, Yasuko

Iwasaki, Genji

Iimori, Takamasa

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00391a073

An asymmetric synthesis of (+)-PS-5 (1) has been accomplished by a route utilizing the anti-selective boron enolate-imine condensation reaction with extremely high asymmetric induction.

Full text of DOI:10.1021/jo00391a073

Products guided by the article

Product name:(2S,3R)-2-Ethyl-3-((S)-1-phenyl-ethylamino)-5-trimethylsilanyl-pent-4-ynethioic acid S-phenyl ester

Cas No:109278-33-3

R&D Labs maybe for 109278-33-3

Jiangsu Willing Bio-Tech Co ltd

website:http://www.willingbio.com/

Contact:+86 18796908173

Address:No 18 Guoqiao Road
Wuxi D-Stone International Co., Ltd.

Contact:+86-510-82740567

Address:21F Hengtong Int'l Centre, 215Zhongshan Road, Wuxi, Jiangsu,China
Jinan Trio PharmaTech Co., Ltd

Contact:86-531-88811783；+(0)13153010282

Address:2766 Yingxiu Road, Jinan High-Tech Zone, China
DU-HOPE INTERNATIONAL GROUP

Contact:+86-25-52346955

Address:199,JIANYE ROAD,NANJING,CHINA
JiangXi Hong Run Chemical Co., Ltd

Contact:+86-0791-88521351

Address:XingHuo industrial zone in YongXiu county

Relevant to this article

Synthesis and evaluation of fluoroquinolone derivatives as substrate-based inhibitors of bacterial efflux pumps

Doi:10.1016/j.ejmech.2008.01.042
(2008)
Doi:10.1002/ardp.19592920205
(1959)
Highly regioselective tandem formal substitution and decarboxylation of 2-acyl-1-chlorocyclopropanecarboxylates with sodium sulfinates

Doi:10.1016/j.tet.2016.04.062
(2016)
Paclitaxel succinate analogs: Anionic and amide introduction as a strategy to impart blood-brain barrier permeability

Doi:10.1016/j.bmcl.2008.09.103
(2008)
Chelation-assisted, copper(II)-acetate-accelerated azide-alkyne cycloaddition

Doi:10.1021/jo101305m
(2010)
Di-, tri-, tetra-, and hexanuclear copper(ll) mono-organophosphates: Structure and nuclearity dependence on the choice of phosphorus substituents and auxiliary n-donor ligands

Doi:10.1021/ic801532y
(2009)

Article Doi