SYNTHESIS OF 5-SUBSTITUTED 4-O-METHYL TETRAMATES

DOI: 10.1016/S0040-4039(00)85192-8

Source and publish data:

Tetrahedron Letters p. 5285 - 5288 (1986)

Update date:2022-08-04

Topics:

Authors:

Jones, Raymond C.F

Bates, Andrew D.

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Article abstract of DOI:10.1016/S0040-4039(00)85192-8

4-Methoxy-Δ³-pyrrolin-2-ones (4-O-methyl tetramates) are alkylated at C-5 via a lithio-derivative; an N-substituent may be introduced either during or after heterocycle formation.

Full text of DOI:10.1016/S0040-4039(00)85192-8

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