
Tetrahedron Letters p. 5285 - 5288 (1986)
Update date:2022-08-04
Topics:
Jones, Raymond C.F
Bates, Andrew D.
4-Methoxy-Δ3-pyrrolin-2-ones (4-O-methyl tetramates) are alkylated at C-5 via a lithio-derivative; an N-substituent may be introduced either during or after heterocycle formation.
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