SYNTHESIS AND EXPERIMENTAL ANTI-TUMOR ACTIVITIES OF 6-ALKYL (OR ARYL) THIO 5-DEAZAPTERIDINES

DOI: 10.1016/0223-5234(87)90008-0

Source and publish data:

European Journal of Medicinal Chemistry p. 135 - 138 (1987)

Update date:2022-09-26

Topics: Synthesis Anti-tumor activities

Authors:

Pochat, Francis

Lavelle, Francois

Fizames, Christian

Zerial, Aurelio

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Article abstract of DOI:10.1016/0223-5234(87)90008-0

6-(p-Bromophenylthio)-5-methyl-2,4,7-triaminopyrido<2,3-d>pyrimidine was found to be active on P388 and L1210 leukemias while 6-alkylthio derivatives were inactive. -- anti-tumor activity / pyridopyrimidine / 5-deazapteridines

Full text of DOI:10.1016/0223-5234(87)90008-0

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