Tetrahedron p. 3851 - 3862 (1986)
Update date:2022-07-30
Topics:
El-Baba, S.
Nuzillard, J. M.
Poulin, J. C.
Kagan, H. B.
Monodehydropeptides with the dehydroaminoacid fragment in C-terminal or N-terminal position were synthetized as well as a family with the general formula Ac-ΔPhe-(Gly)n-Leu-OR (n = 0-2, R = H or Me).Asymmetric reduction of these compounds catalyzed by chiral rhodium complexes was investigated.The results were discussed in terms of double asymmetric induction.A method was developped to avoid the use of both enantiomers of the substrate or of the catalyst, it consists in the total reduction of a racemic dehydropeptide.The products distribution gives access to the two desired facial selectivities.
View MoreContact:+86-371-55981030
Address:Room 1571, Macalline Soho, No.1, Shangdu Road, Zhengzhou, Henan
Zhonghao (dalian) Research and Design Institute of Chemical Industry Co., Ltd
Contact:+86 411 84674606
Address:201, Huangpu Road , Shahekou District, Dalian ,116023-China
Beijing Tianjia Chemical Science & Technology Co.,Ltd
Contact:86-0550-2392698
Address:No.388, Shiliang Road (East),
Jinhua City Mingzhu Pharmaceutical Co.,Ltd.
Contact:15857995878 0579-82207761
Address:No.169 Shenze Road, New Area,Jinpan Development Zone, Jinhua
Shanghai Send Pharmaceutical Technology Co., Ltd.
website:http://www.shsendpharma.com
Contact:021-58088081, +8613585868794
Address::Room A601, Building 1,NO. 800 Qingdai Road Pudong District Shanghai,China
Doi:10.1016/bs.mie.2019.04.009
(2019)Doi:10.1016/j.apcata.2009.11.003
(2010)Doi:10.1002/adsc.201100273
(2011)Doi:10.1021/jo801556p
(2009)Doi:10.1016/j.tetlet.2013.10.052
(2013)Doi:10.1002/chem.200800534
(2008)
