Synthesis and Physicochemical Properties of Thiadiazolopyrimidinesulfonamides and Thiadiazolotriazinesulfonamides as Candidates for Topically Effective Carbonic Anhydrase Inhibitors

DOI: 10.1021/jm00394a021

Source and publish data:

Journal of Medicinal Chemistry p. 2058 - 2062 (1987)

Update date:2022-08-05

Topics:

Authors:

Katritzky, Alan R.

Caster, Kenneth, C.

Maren, Thomas H.

Conroy, Curtis W.

Bar-Ilan, Amir

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00394a021

A series of bicyclic 1,3,4-thiadiazolo<3,2-a>pyrimidine- and 1,3,4-thiadiazolo<3,2-a>triazine-7-sulfonamides were synthesized from 5-amino-1,3,4-thiadiazole-2-sulfonamide and evaluated for topical efficacy as ocular hypotensive agents.The compounds were t

Full text of DOI:10.1021/jm00394a021

Products guided by the article

Product name:5--1,3,4-thiadiazole-2-sulfonamide

Cas No:109927-24-4

R&D Labs maybe for 109927-24-4

ZIBO GREEN TRADE CO., LTD

Contact:0543-3317184

Address:No.1401, Unit 1, Global building, Binzhou city, shandong PRC.
Shanghai KFSL Pharmaceutical Technology Co.,Ltd.

Contact:+86-21-39971718

Address:859 jiadingchengliu shanghai
FOSHAN NANHAI ZHONGNAN PHARMACEUTICAL FACTORY

Contact:0086-0757-85609331

Address:XIAHENGTIAN INDUSTRIAL ZONE,SHAYONG VILLAGE,LISHUI TOWN
HANGZHOU TOYOND BIOTECH CO., LTD

Contact:+86-571-86965177

Address:No. 189, Fengqi East Road, Hangzhou, China
Tianjin Hedong Red Cliff Chemical Reagent Factory

Contact:+86-022-84780548

Address:Li Ming Zhuang Gong Ye Yuan,Dongli District,Tianjin,China

Relevant to this article

The Chemistry of Allene Cation Radicals Probed by the Use of Theoretical and Electron-Transfer Photochemical Methods

Doi:10.1021/jo00228a017
(1987)
Synthesis and Co-ordination Chemistry of the Macrocycle 1,4,7-Triisopropyl-1,4,7-triazacyclononane

Doi:10.1039/DT9930000083
(1993)
Synthesis of cyclobutenes by highly selective transition-metal-catalyzed ring expansion of cyclopropanes

Doi:10.1002/anie.200803910
(2008)
A convenient chemo-enzymatic synthesis and ¹⁸F-labelling of both enantiomers of trans-1-toluenesulfonyloxymethyl-2-fluoromethyl-cyclopropane

Doi:10.1039/b812777h
(2008)
Primary amino acid lithium salt as a catalyst for asymmetric Michael addition of isobutyraldehyde with β-nitroalkenes

Doi:10.1039/b814804j
(2008)
TOTAL SYNTHESIS OF A UNDECASACCHARIDE: A TYPICAL CARBOHYDRATE SEQUENCE FOR THE COMPLEX TYPE OF GLYCAN CHAINS OF A GLYCOPROTEIN

Doi:10.1016/S0040-4039(00)85314-9
(1986)

Article Doi