Monatshefte fur Chemie p. 1073 - 1080 (1986)
Update date:2022-08-03
Topics:
Berner, Heinz
Vyplel, Hermann
Schulz, Gerhard
Schneider, Helmut
The reaction of pleuromutilin-22-O-tosylat(2) with EtZnI afforded a mixture of the 12-epimeric compounds 2 and 3.A reversible retro-en-reaction of the homoallylic system is discussed as a possible mechanistic pathway.The structure assignment is based on 1H- and 13C-NMR spectroscopic data. - Keywords: Pleuromutilin; Inversion of configuration; Reversible retro-en-cleavage; Simmons-Smith-reaction; Type I-"metallo-en"-reaction
View MoreShanghai Mio Chemical Co., Ltd
Contact:0086 21- 64401188-622
Address:16 Floor NO.2 Jiefang Building, No. 4855 Dushi Road, 201100 Shanghai, P.R.China
Chengdu Sino-Strong Pharmaceutical Co.,Ltd.
website:http://www.sino-strong.com.cn
Contact:+86-28-82666753
Address:459 West haike road,Cross-straits technological industry park, Wenjiang district,Chengdu, P.R.China
Contact:+86-27-87204219, +86-27-87215023
Address:2402, HuiGu Space-time Building, 8 Forest Road, East Lake Hi-Tech Development Zone
SHANDONG QINGYUNCHANGXIN CHEMICAL SCIENCE-TECH CO.,LTD
Contact:86-21-60560171
Address:1689Donghuan Rade,Qingyun County, Dezhou City, Shandong,China
Hubei Lansun Biochemical Pharmaceutical Co., Ltd
Contact:714-6395977
Address:No. 81 Pengcheng Avenue, economic and technological development zone, Huangshi City, Hubei Province,China
Doi:10.1039/jr9640003330
(1964)Doi:10.1007/BF00953852
(1987)Doi:10.1002/adsc.201801423
(2019)Doi:10.1016/j.bmc.2008.02.055
(2008)Doi:10.1021/jo00238a036
(1988)Doi:10.1021/ja00016a003
(1991)
