Monatshefte fur Chemie p. 1073 - 1080 (1986)
Update date:2022-08-03
Topics:
Berner, Heinz
Vyplel, Hermann
Schulz, Gerhard
Schneider, Helmut
The reaction of pleuromutilin-22-O-tosylat(2) with EtZnI afforded a mixture of the 12-epimeric compounds 2 and 3.A reversible retro-en-reaction of the homoallylic system is discussed as a possible mechanistic pathway.The structure assignment is based on 1H- and 13C-NMR spectroscopic data. - Keywords: Pleuromutilin; Inversion of configuration; Reversible retro-en-cleavage; Simmons-Smith-reaction; Type I-"metallo-en"-reaction
View Morewebsite:http://www.cartoonchem.com/
Contact:+86-25-58074918
Address:Room 2109, RuiHua Business Center,315 South ZhongShan Road, Nanjing 210001, China
Tianjin Te-An Chemtech Co., Ltd.(expird)
Contact:+86-22-65378638
Address:A5-8, No.80 Haiyun Street, TEDA
Binzhou Holly Pharmaceutical Co.,Ltd.
Contact:74517
Address:No.15 Dapu Road,Huangpu District Shanghai,P.R.China
AstaTech ( Chengdu) BioPharmaceutical Corp.
website:http://www.astabiochem.cn/
Contact:+86-15198215156-15198215156
Address:SICHUAN CHENGDU
Xi'an caijing Opto-Electrical Science & Technology Co., LTD
Contact:+86-29-88294447
Address:NO.168 Zhangba Rd. East, Xi'an, P.R.China
Doi:10.1039/jr9640003330
(1964)Doi:10.1007/BF00953852
(1987)Doi:10.1002/adsc.201801423
(2019)Doi:10.1016/j.bmc.2008.02.055
(2008)Doi:10.1021/jo00238a036
(1988)Doi:10.1021/ja00016a003
(1991)
