Differentiating n-terminal aspartic and isoaspartic acid residues in peptides

DOI: 10.1021/ac201223d

Source and publish data:

Analytical Chemistry p. 6675 - 6682 (2011)

Update date:2022-09-26

Topics:

Authors:

Sargaeva, Nadezda P.

Lin, Cheng

Oconnor, Peter B.

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Article abstract of DOI:10.1021/ac201223d

Formation of isoaspartic acid (isoAsp) is a common modification of aspartic acid (Asp) or asparagine (Asn) residue in proteins. Differentiation of isoAsp and Asp residues is a challenging task owing to their similar properties and identical molecular mass

Full text of DOI:10.1021/ac201223d

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