Conversion of 1,4-Dihydrobenzoic Acids to Polyformylbenzenes under Vilsmeier Reaction Conditions

Article abstract of DOI:10.1055/s-1987-27890

1,4-Dihydrobenzoic acids 1a-e are converted by a one-pot reaction to benzene- mono-, di- and tricarboxaldehydes under Vilsmeier reaction conditions in yields ranging from 6 to 65percent.The same methodology also serves to give naphthalene-1,3-dicarboxaldehyde (2f) from 1,4-dihydro-1-naphthoic acid (1f) in 91percent yield.