
Tetrahedron p. 5895 - 5900 (1986)
Update date:2022-07-29
Topics:
Mori, Kenji
Kato, Minoru
All of the four possible stereoisomers of hernandulcin <6-(1'-hydroxy-1',5'-dimethyl-4'-hexenyl)-3-methyl-2-cyclohexenone> were synthesized starting from the enantiomers of limonene.The absolute configuration of the naturally occuring and sweet-tasting (+)-hernandulcin was established as 6S,1'S.Other stereoisomers were not sweet at all.
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