AN EFFICIENT SYNTHESIS OF 1-PHENYL-1-PIPERIDINO-trans-4-METHYLCYCLOHEXANE: UNANTICIPATED TOTAL STEREOSELECTIVITY IN THE CATALYTIC HYDROGENATION OF AN OLEFIN

DOI: 10.1016/S0040-4039(01)80977-1

Source and publish data:

Tetrahedron Letters p. 741 - 744 (1987)

Update date:2022-07-29

Topics:

Authors:

Vinick, F.J.

Nowakowska, J.

Jung, S.

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Article abstract of DOI:10.1016/S0040-4039(01)80977-1

A superior synthesis of the title compound, 1-phenyl-1-piperidino-trans-4-methylcyclohexane, is reported.The key step, the catalytic hydrogenation of 1-phenyl-1-piperidino-4-methylenecyclohexane hydrochloride, proceeds with unusual stereospecificity via a

Full text of DOI:10.1016/S0040-4039(01)80977-1

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