4-N-Hydroxy-L-2,4-diaminobutyric acid. A strong inhibitor of glutamine synthetase

DOI: 10.1021/jm00397a037

Source and publish data:

Journal of Medicinal Chemistry p. 480 - 483 (1988)

Update date:2022-08-04

Topics: Chemical term Explanation Experimental term

Authors:

Fushiya Fushiya

Maeda Maeda

Funayama

Nozoe Nozoe

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00397a037

Analogues of glutamic acid were synthesized and evaluated for their inhibitory activity toward glutamine synthetase (EC 6.3.1.2; GS). The title compound, 4-N-hydroxy-L-2,4-diaminobutyric acid (NH-DABA), showed a potent inhibitory activity against GS from

Full text of DOI:10.1021/jm00397a037

Products guided by the article

Product name:Butanoic acid, 4-[(phenylmethoxy)amino]-2-[[(phenylmethoxy)carbonyl]amino]-, phenylmethyl ester, (S)-

Cas No:111772-95-3

R&D Labs maybe for 111772-95-3

Shanghai PuYi Chem-Tech Co.,Ltd.

Contact:+86-21-57687505-227

Address:3 Floor, Building 11, No 201 MinYi Road, Songjiang District, Shanghai 201612, China
Wuhan Shengmao Corp

website:http://www.shengmaochem.com

Contact:86-27-82853423, 82819281

Address:Rm 202, A Unit Huaqiao Building No. 2, Lihuangpi Road, Wuhan, China
Shandong Yuanli Science and Technology Co., Ltd.

Contact:86-0536-6777557

Address:Zhuliu Industiral Park,Changle County
xujianqiang

Contact:86-21-57725962

Address:shanghai
Jiangxi Huashi Pharmaceutical Co., Ltd

Contact:+86-795-4509628

Address:No.199, Ningbo Avenue, Fengxin industrial park, Fengxin county, Yichun city, Jiangxi

Relevant to this article

Synthesis of new substituted saturated γ -lactones from 2-(2,2-dimethyl-5-oxotetrahydrofuran-3-yl)acetyl chloride

Doi:10.1515/hc-2012-0017
(2012)
Aryloxy cyclohexyl imidazoles: A novel class of antileishmanial agents

Doi:10.1016/j.bmcl.2008.11.094
(2009)
Yttrium–Benzyl Complexes Bearing Chiral Iminophosphonamide Ligands: Synthesis and Application in Catalytic Asymmetric Amine-Silane Dehydrocoupling Reactions

Doi:10.1002/adsc.201700327
(2017)
FACILE SYNTHESIS AND HERBICIDAL ACTIVITIES OF NOVEL FLUOROQUINOXALINES

Doi:10.3987/R-1987-05-1215
(1987)
Organoboranes. 39. Convenient procedures for the preparation of methylboronic acid and trimethylboroxin

Doi:10.1021/om00124a002
(1985)
PREPARATION OF t-BUTYL 4-DIETHYLPHOSPHONO-3-OXOBUTANETHIOATE AND USE IN THE SYNTHESIS OF (E)-4-ALKENYL-3-OXOESTERS AND MACROLIDES

Doi:10.1016/S0040-4039(00)95725-3
(1987)

Article Doi