4-N-Hydroxy-L-2,4-diaminobutyric acid. A strong inhibitor of glutamine synthetase

DOI: 10.1021/jm00397a037

Source and publish data:

Journal of Medicinal Chemistry p. 480 - 483 (1988)

Update date:2022-08-04

Topics: Chemical term Explanation Experimental term

Authors:

Fushiya Fushiya

Maeda Maeda

Funayama

Nozoe Nozoe

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Article abstract of DOI:10.1021/jm00397a037

Analogues of glutamic acid were synthesized and evaluated for their inhibitory activity toward glutamine synthetase (EC 6.3.1.2; GS). The title compound, 4-N-hydroxy-L-2,4-diaminobutyric acid (NH-DABA), showed a potent inhibitory activity against GS from

Full text of DOI:10.1021/jm00397a037

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