Chemistry of Heterocyclic Compounds p. 325 - 332 (1987)
Update date:2022-08-03
Topics:
Zakhs, V. E.
Yakovlev, I. P.
Smorygo, N. A.
Gindin, V. A.
Ivin, B. A.
1H, 13C NMR, IR, and UV spectra have been studied for solutions of a number of potentially tautomeric 2-aryl-1,3-oxazine-4,6-diones and their 5-methyl substituted analogs with variation of substitutent at the para position of the benzene ring, as well as compounds with a fixed structure that simulates possible tautomeric forms.The data have been compared with the results of quantum chemical calculations carried out in SSO MO LCAO approximation by the CNO, CNDO/2, and MPNDO/3 methods.In DMSO and THF solution the test compounds exist predominantly as 2-aryl-4-hydroxy-6H-1,3-oxazin-6-ones.The para substituent in the benzene ring does not effect the composition of the tautomer mixture significantly.
View MoreXi'an Costrong Pharmaceutical Co., Ltd.
Contact:029- 68576496
Address:Room 2004,Shuibao Building,No.190,South Erhuan Rd, Yanta District,Xi'an,Shaan Xi,China
Contact:+86-519-86339586,13584329896
Address:Changzhou Scientific and Education Park
Rizhao Lanxing Chemical Indusrial Co.,Ltd
Contact:86-633-2616708
Address:NO.15 West road Shenglan, Lanshan district, Rizhao City
Shanghai united Scientific Co.,Ltd.
Contact:+86-21-53535353
Address:28F No.900 huaihai Road Shanghai China
Suzhou Jingye Medicine & Chemical Co., Ltd
website:http://www.jingyechem.cn
Contact:+86-512-66658588
Address:No. 88, Sanlian Street, Jinfeng Road, Suzhou New District, Jiangsu Province, P. R. China
Doi:10.1016/S0040-4020(01)90025-0
(1987)Doi:10.1016/j.bmc.2008.12.012
(2009)Doi:10.1021/acs.jmedchem.6b01644
(2017)Doi:10.1139/V08-074
(2009)Doi:10.1021/ja00209a063
(1988)Doi:10.1016/S0022-1139(00)83408-9
(1985)