EASY ALKYLATION OF PURINE BASES BY SOLID-LIQUID PHASE TRANSFER CATALYSIS WITHOUT SOLVENT. STRUCTURAL ANALYSIS BY 2D HETERONUCLEAR 1H 13C CORRELATED NMR SPECTROSCOPY

DOI: 10.1016/S0040-4020(01)86791-0

Source and publish data:

Tetrahedron p. 2101 - 2108 (1987)

Update date:2022-09-26

Topics:

Authors:

Platzer, Nicole

Galons, Herve

Bensaid, Younes

Miocque, Marcel

Bram, Georges

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Article abstract of DOI:10.1016/S0040-4020(01)86791-0

Solid-liquid PTC without added organic solvent promotes alkylation of purine derivatives leading in particular to an efficient synthesis of the antiviral DHPA.The location of the substituent on the ring was determined by analysis of coupling interactions

Full text of DOI:10.1016/S0040-4020(01)86791-0

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