
Journal of Organic Chemistry p. 1380 - 1383 (1988)
Update date:2022-08-04
Topics:
McCloskey, Patrick J.
Schultz, Arthur G.
The first total synthesis of a trans-decahydroquinoline alkaloid derivative, (+)-perhydro-219A, is described.Key steps of the synthesis include the directed metalation-ethylation of 6-methylpyrrolobenzodiazepine-5,11-dione 2 to give the C(6)-n-propyl deri
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