Synthesis of Bicyclic Cis Fused Dihydrofuran Derivatives via the Intramolecular Mitsunobu Reaction

Article abstract of DOI:10.1016/0040-4039(95)00732-R

Stereoselective dehydrative alkylation/annulationb of hydroxy β-diketones, β-ketoesters or β-diesters using Mitsunobu conditions (Bu3P/DEAD) proceeds under mild and essentially neutral conditions affording cis fused bicyclic dihydrofurans in good yields.