
Tetrahedron Letters p. 393 - 396 (1994)
Update date:2022-07-30
Topics:
Robl, Jeffrey A.
A method for the stereoselective generation of 7,6- and 7,5-fused bicyclic lactams of type 1 has been developed. The key step involves intramolecular N-acyliminium ion cyclization of N-acyl enamine 2 to generate the core bicyclic framework. Lactams of typ
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