REGIOSPECIFIC SYNTHESIS OF 2'-DEOXY-2',2''-DIDEUTERIO NUCLEOSIDES

DOI: 10.1016/S0040-4020(01)86822-8

Source and publish data:

Tetrahedron p. 2355 - 2368 (1987)

Update date:2022-07-30

Topics:

Authors:

Wu, J-C.

Bazin, H.

Chattopadhyaya, J.

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Article abstract of DOI:10.1016/S0040-4020(01)86822-8

Two routes have been devised for the first synthesis of 2',2''-dideuterio-2'-deoxynucleosides.First route involves the oxidation of an appropriately 3',5'-protected ribonucleosides with CrO₃-pyridine-acetic anhydride complex, followed by direct

Full text of DOI:10.1016/S0040-4020(01)86822-8

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