The Addition of Organolithium Reagents to Quinone Silyl Methyl Monoketals. A Useful Expedient in the Synthesis of p-Quinols Having Acid-Sensitive Groups

Article abstract of DOI:10.1021/jo00246a013

Acid hydrolyses of dimethyl ketals 4-alkyl- and 4-aryl-4-hydroxy-2,5-cyclohexadienones having an acid-sensitive functionality often afford low or no yields of the respective 4-substituted 4-hydroxy-2,5-cyclohexadienones (p-quinols).However, addition of me