Chemistry of Heterocyclic Compounds p. 1123 - 1129 (1987)
Update date:2022-08-04
Topics:
Nanavyan, I. M.
Kuz'menko, V. V.
Pozharskii, A. F.
Klyuev, N. A.
By treating 8-aminotheophylline with hydroxylamine-O-sulfonic acid in aqueous alkali we have obtained 7,8-diaminotheophylline and studied its reactions with benzaldehyde, 1,2-dicarbonyl compounds, and acylating agents.We have established that in reactions with electrophiles, the N-amino group in 7,8-diaminotheophylline is more active than the amino group situated at the 8-position.An unexpected self-condensation of two molecules of 7,8-diaminotheophylline has been found in acid medium, leading to purino<8,7g>-7-azapteridine derivatives.
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Doi:10.1016/j.bmc.2014.07.006
(2014)Doi:10.1039/c5ob00037h
(2015)Doi:10.1002/hlca.201200528
(2012)Doi:10.1021/jo00251a033
(1988)Doi:10.1021/ja01610a017
(1955)Doi:10.1016/S0040-4039(00)96527-4
(1987)
