Synthesis and antifungal activities of phenylenedithioureas

DOI: 10.1016/j.bmcl.2003.11.044

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 653 - 656 (2004)

Update date:2022-08-02

Topics:

Authors:

Phuong, Truong

Khac-Minh, Thai

Van Ha, Nguyen Thi

Ngoc Phuong, Huynh Thi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/j.bmcl.2003.11.044

A total of 20 new phenylenedithiourea derivatives was synthesized by reaction of phenylenediisothiocyanates with aromatic amines as aminobenzoic, aminosalicylic acid and their derivatives. Their chemical structures were confirmed by elemental analysis, IR spectrometry and ¹H NMR. The compounds were screened for in vitro antifungal, antibacterial activities and some of them have strong antifungal activities comparable to the activity observed for ketoconazole.

Full text of DOI:10.1016/j.bmcl.2003.11.044

Products guided by the article

Product name:Benzoic acid, 4,4'-[1,4-phenylenebis(iminocarbonothioylimino)]bis[2-hydroxy-

Cas No:115189-56-5

R&D Labs maybe for 115189-56-5

Huangshi Shennong Chemical Technology Co., Ltd

Contact:+86-714-3072290

Address:Eastern industrial park , Tieshan district , Huangshi city ,Hubei province , China
Chengdu Green Young Biopharmaceutical INC

Contact:+86-28-85337952

Address:1-B-26,Tianhe Industry Park, No.1480 of Tianfu Road,Chengdu,P.R.China,610000
Xian Changyue Biological Technology Co., Ltd.

website:https://www.xachangyue.com/

Contact:+86-029-88211911

Address:Keji Road NO.70
Weifang Yukai Chemical Co.,Ltd.

website:http://www.yukaichem.com/en.html

Contact:+86-536-8865336

Address:binhai economic development zone，262737 shangdong，china
Hangzhou Haichem Co.,Ltd.

Contact:+86-571-86025531 / 86024803

Address:1218-24 Guangyin Mansion,42 Fengqi East Road

Relevant to this article

Bioactive hepta- and penta-coordinated supramolecular diorganotin(IV) Schiff bases

Doi:10.1016/j.jorganchem.2013.05.019
(2013)
Synthesis of 1,4,5-trissulphated and 1,4,5-trissulphamoylated myo-inositols: Isosteric myo-inositol 1,4,5-trisphosphate analogues

Doi:10.1016/S0040-4039(00)97207-1
(1990)
Evidence of solubility of the acetylide ion C₂^2-: Syntheses and crystal structures of K₂C₂·2NH ₃, Rb₂C₂·2NH₃, and Cs ₂C₂·7NH₃

Doi:10.1002/anie.201206349
(2012)
5-(2-Pyrimidinyl)-imidazo[1,2-a]pyridines are antibacterial agents targeting the ATPase domains of DNA gyrase and topoisomerase IV

Doi:10.1016/j.bmcl.2009.07.141
(2009)
Novel strategy for synthesis of substituted benzimidazo[1,2-a]quinolines

Doi:10.1021/ol4017723
(2013)
A pentiptycene-derived light-driven molecular brake

Doi:10.1021/ol800689a
(2008)

Article Doi