Synthesis p. 1108 - 1110 (1987)
Update date:2022-08-03
Topics:
Gajda, Tadeusz
1-Primary, 3-secondary 1,3-alkanediols can be selectively aminated at C-1 via OH/NH2 exchange by reaction with diethyl N-Boc-phosphoramidate in ether using triphenylphosphine/diethyl diazenedicaboxylate as condensing agent, and treatment of the resultant diethyl N-Boc-N-(3-hydroxyalkyl)phosphoramidates with 4-nitrobenzoyl chloride/pyridine, followed by dephosphorylation with hydrogen chloride in ethyl acetate.The reaction sequence affords the hydrochlorides of 3-aminoalkyl 4-nitrobenzoates in good yields.
View MoreYuan Shi(SuQian)Biotechnology Co.,Ltd
website:http://www.yuanshibio.com
Contact:+86-527-84226672
Address:jiangsu suqian
Hebei Think-Do Environment Co., Ltd
website:http://www.thinkdo-environment.com
Contact:0311-86510809-
Address:No 6, Shilian Middle Street, Circular Chemical Industry Park
Penglai Qianwei Chemical Co., Ltd.
Contact:86-535-3357802
Address:Shahelu (north), Penglai, Shandong, China
JIANGXI AIFEIMU TECHNOLOGY CO.，LTD
Contact:+86-570-6040289
Address:FINECHEMICAL PARK,ZIBU TOWN,WANNIAN COUNTY,JIANGXI PROV.,CHINA,ZIP
Anyang Double Circle Auxiliary CO.,LTD
Contact:0086-134 6082 4403
Address:dongfeng road, anyang city, henan province,china
Doi:10.1016/j.jfluchem.2008.04.012
(2008)Doi:10.1016/S0040-4039(00)86723-4
(1988)Doi:10.3109/14756366.2015.1029470
(2016)Doi:10.1016/j.bmcl.2009.02.110
(2009)Doi:10.1007/BF00768251
(1988)Doi:10.1016/j.jorganchem.2008.12.011
(2009)
