Green Chemistry p. 1685 - 1691 (2017)
Update date:2022-08-04
Topics: Synthesis Green chemistry Peptide Catalyst Solvent Atom economy Microwave irradiation Environmental Impact Peptide bond Sustainable
Lawrenson, Stefan B.
Arav, Roy
North, Michael
The synthesis of peptides by amide bond formation between suitably protected amino acids is a fundamental part of the drug discovery process. However, the required coupling and deprotection reactions are routinely carried out in dichloromethane and DMF, b
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