Synthesis and pharmacological properties of 'soft drug' derivatives related to perhexiline

DOI: 10.1021/jm00120a007

Source and publish data:

Journal of Medicinal Chemistry p. 2289 - 2296 (1988)

Update date:2022-08-03

Topics:

Authors:

Marciniak

Decolin Decolin

Leclerc Leclerc

Decker Decker

Schwartz

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Article abstract of DOI:10.1021/jm00120a007

In the hope of reducing the toxicity of perhexiline, a series of 27 cyclohexylaralkylamines II based on the 'soft drug' concept and incorporating an amide function were synthesized. In a preliminary screening, compounds were evaluated for their α-adrenoly

Full text of DOI:10.1021/jm00120a007

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