Platelet activating factor antagonists: Synthesis and structure-activity studies of novel PAF analogues modified in the phosphorylcholine moiety

DOI: 10.1021/jm00121a012

Source and publish data:

Journal of Medicinal Chemistry p. 56 - 64 (1989)

Update date:2022-08-03

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Authors:

Takatani

Yoshioka

Tasaka Tasaka

Terashita

Imura Imura

Nishikawa

Tsushima

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Article abstract of DOI:10.1021/jm00121a012

New analogues of platelet activating factor (PAF), in which the phosphate and trimethylammonium moieties were replaced with an acylcarbamoyl moiety and a quaternary cyclic ammonium group, were synthesized. Their biological activities as PAF antagonists we

Full text of DOI:10.1021/jm00121a012

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