Platelet activating factor antagonists: Synthesis and structure-activity studies of novel PAF analogues modified in the phosphorylcholine moiety

DOI: 10.1021/jm00121a012

Source and publish data:

Journal of Medicinal Chemistry p. 56 - 64 (1989)

Update date:2022-08-03

Topics:

Authors:

Takatani

Yoshioka

Tasaka Tasaka

Terashita

Imura Imura

Nishikawa

Tsushima

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00121a012

New analogues of platelet activating factor (PAF), in which the phosphate and trimethylammonium moieties were replaced with an acylcarbamoyl moiety and a quaternary cyclic ammonium group, were synthesized. Their biological activities as PAF antagonists we

Full text of DOI:10.1021/jm00121a012

Products guided by the article

Product name:Carbonic acid 2-benzyloxy-3-octadecyloxy-propyl ester phenyl ester

Cas No:116953-25-4

R&D Labs maybe for 116953-25-4

Nanjing Norris Pharm Technology Co., Ltd.

Contact:+86-13901585132

Address:2 Qiande Road, Jiangning sciencepark Hi-Tech Zone, Nanjing, P.R.China
Hubei Sky Lake Chemical Co., Ltd.

Contact:+86-27-87385545

Address:Te-2, Xijiao Chemical Park, Yuekou Town, Tianmen, Hubei, China.
Puyang Huicheng Electronic Material Co., Ltd

website:http://huichengchem.weba.testwebsite.cn/index_en.html

Contact:+86-393-8910800

Address:West Section Shengli Road, Puyang457000, China
Tianjin Ingenochem Technology Co.,Ltd

Contact:+86-22-23677060

Address:Hitech Green Industry Park K2-9-602, Nankai district
Guangzhou PI & PI Biotech Inc. Ltd.

Contact:+86-20-81716320

Address:Suite 501,198 Kaiyuan Ave.,Science City, Guangzhou,China

Relevant to this article

An efficient asymmetric synthesis of 3S,4S-3-acylamino-4-hydroxymethylazetidin-2-ones

Doi:10.1016/S0040-4039(01)93751-7
(1989)
Fused Imidazoles: I. Synthesis of 6,7-Dihydro-5H-pyrrolo[1,2-a]imidazole Derivatives

Doi:10.1134/S107042801806012X
(2018)
Facile Ramberg-Baecklund reactions for the synthesis of 2,3-disubstituted cyclopentenones; a short synthetic route to tetrahydrodicranenone B

Doi:10.1039/C39880000454
(1988)
Tetraphenylborate Anion Oxidation by Acidic Co²⁺ Cations: Synthesis and Properties of Pyridine-Cobalt(I) Complexes

Doi:10.1039/c39880001100
(1988)
Doi:10.1002/hlca.19600430158
(1960)
Mechanism of the cross-coupling reaction of phenyl iodide and methylmagnesium iodide catalyzed by trans-PdPh(I)(PEt₂Ph)₂

Doi:10.1021/om00103a023
(1989)

Article Doi