A base labile protecting group for peptide synthesis: 2,2,-Bis(4'-nitrophenyl)ethan-1-oxycarbonyl urethanes

DOI: 10.1016/S0040-4020(01)81953-0

Source and publish data:

Tetrahedron p. 8001 - 8024 (1991)

Update date:2022-08-05

Topics:

Authors:

Ramage Ramage

Blake Blake

Florence

Gray Gray

Raphy Raphy

Roach Roach

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(01)81953-0

A base labile urethane (Bnpeoc) group derived from 2,2,-bis(4'-nitrophenyl)ethan-1-ol has been developed as an amine protecting group. This protecting group may be cleaved using the reagents DBN, DBU, DBU/HOAc and piperidine. The preparations of N(α)-Bnpeoc amino acids and applications to peptide/glycopeptide synthesis are described.

Full text of DOI:10.1016/S0040-4020(01)81953-0

Products guided by the article

Product name:Glycine, N-[N-[N-[[2,2-bis(4-nitrophenyl)ethoxy]carbonyl]-L-alanyl]-L-phenylalanyl]- , methyl ester

Cas No:117368-00-0

R&D Labs maybe for 117368-00-0

Wuhan Soleado Technology Co.,Ltd.

Contact:86-2783341481 18971291927

Address:RM2405 Unit 1 Builing 1, Taiyin Tower, Changqing Road,Wuhan China
shanghai hekang chemical co.ltd

Contact:021-54173790

Address:328 WuHe Road, Building #A, 2nd Floor, Minhang, Shanghai 201109, China
Anqing World Chemical Co., Ltd.

Contact:+86-556-5800026

Address:Daguan Economic Development Zone of circular economy industrial park Anqing City Anhui province
New Forms

Contact:+31-24-3886056

Address:Binderskampweg 29 Unit 36
Lishui Nanming Chemical Co., Ltd(expird)

Contact:+86-0578-2134101，2697830

Address:No.19 Tongji Road Shuige Industrial zone

Relevant to this article

Development of practical syntheses of potent non-nucleoside reverse transcriptase inhibitors

Doi:10.1016/j.tet.2009.03.084
(2009)
A simple one-pot synthesis of functionalised 6-(indol-3-yl)-2,2′-bipyridine derivatives via multi-component reaction under neat condition

Doi:10.1016/j.tetlet.2009.04.121
(2009)
ENANTIOSELECTIVE HYDROSILYLATION OF ACETOPHENONE WITH RHODIUM /OXAZOLINES CATALYSTS

Doi:10.1016/S0040-4039(01)93469-0
(1989)
Hypervalent iodine mediated oxidation of 1,2-diaminobenzimidazole and its schiff bases: Efficient synthesis of 3-amino-1,2,4-benzotriazine and 2-aryl-1,2,4-triazolo[1,5-a]benzimidazoles

Doi:10.1055/s-0028-1088055
(2009)
Metathesis-like splitting reactions of metallated [36]octaphyrins (1.1.1.1.1.1.1.1): Experimental and computational investigations

Doi:10.1002/chem.200900454
(2009)
SYNTHETIC APPROACH TO BACTERIAL LIPOPOLYSACCHARIDE ,PREPARATION OF TRISACCHARIDE PART STRUCTURES CONTAINING KDO AND 1-DEPHOSPHO LIPID A

Doi:10.1016/S0040-4039(00)86718-0
(1988)

Article Doi