
Tetrahedron p. 8001 - 8024 (1991)
Update date:2022-08-05
Topics:
Ramage
Blake
Florence
Gray
Raphy
Roach
A base labile urethane (Bnpeoc) group derived from 2,2,-bis(4'-nitrophenyl)ethan-1-ol has been developed as an amine protecting group. This protecting group may be cleaved using the reagents DBN, DBU, DBU/HOAc and piperidine. The preparations of N(α)-Bnpeoc amino acids and applications to peptide/glycopeptide synthesis are described.
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(1988)