Tetrahedron p. 2457 - 2470 (1988)
Update date:2022-08-04
Topics:
Arseniyadis, S.
Huang, P. Q.
Piveteau, D.
Husson, H.-P.
The synthesis of 2-cyano-5-oxazolopyrrolidine 3, a chiral pyrrolidine synthon, is described.Conditions were established that permitted sequential chemoselective reactions at the C-2 aminonitrile (electrophilic substitution) and at the C-5 aminoether (nucl
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