Michael additions versus cycloaddition condensations with ethyl nitroacetate and electron-deficient olefins

DOI: 10.1002/chem.200802652

Source and publish data:

Chemistry - A European Journal p. 7940 - 7948 (2009)

Update date:2022-09-26

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Authors:

Trogu, Elena

De Sarlo, Francesco

Machetti, Fabrizio

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Article abstract of DOI:10.1002/chem.200802652

Ethyl nitroacetate (1) reacts with electron-poor olefins in the presence of a base to give either the Michael adducts 3 or the isoxazoline cycloadducts 4, resulting from water elimination. The proportions of the two products depend on the reaction conditi

Full text of DOI:10.1002/chem.200802652

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