3947-76-0

Basic information

• Product Name: 1-METHYLQUINOLINIUM IODIDE
• Synonyms: QUINOLINE METHYL IODIDE;BENZO(B)PYRIDINE METHYL IODIDE;1-METHYLQUINOLINIUM IODIDE;1-BENZAZINE METHYL IODIDE
• CAS NO: 3947-76-0
• Molecular Formula: C₁₀H₁₀N*I
• Molecular Weight: 271.1
• Mol File: 3947-76-0.mol
• Article Data: 42

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-METHYLQUINOLINIUM IODIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-METHYLQUINOLINIUM IODIDE(3947-76-0)
• EPA Substance Registry System: 1-METHYLQUINOLINIUM IODIDE(3947-76-0)

Safety Data

• Hazardous Substances Data: 3947-76-0(Hazardous Substances Data)

Usage

Uses

Quinoline Methyl Idodide is a reagent used in the preparation of chiral boron(III)chelates.

InChI:InChI=1/C10H10N/c1-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3/q+1

Upstream product

• 91-63-4 2-methylquinoline 
• 74-88-4 methyl iodide 
• 948-43-6 N-methylacridinium iodide 
• 90731-53-6 2-(indol-3-yl)-1-methyl-1,2-dihydroquinoline 
• 91-22-5 quinoline 

Downstream Products

• 1228-70-2 2-(1-methyl-1,4-dihydro-quinolin-4-yl)-2-phenyl-propionitrile 
• 887-94-5 1-methyl-2-phenyl-1,2-dihydroquinoline 
• 16021-60-6 1-Methyl-1,2-dihydroquinoline 
• 491-34-9 N-methyl-1,2,3,4-tetrahydroquinoline 
• 2739-16-4 3,4-dihydro-2H-quinoline-1-carbaldehyde 
• 16021-43-5 2-diphenylamino-5-(1-methyl-1,4-dihydro-quinolin-4-yl)-thiazol-4-one 
• 132363-86-1 1-methyl-2-trichloromethyl-1,2-dihydroquinoline 
• 91-22-5 quinoline 
• 114414-78-7 neocryptolepine 

Relevant articles and documents

Genetically Encoded Dual-Color Light-Up RNA Sensor Enabled Ratiometric Imaging of MicroRNA

MicroRNAs (miRNAs) play essential roles in regulating gene expression and cell fate. However, it remains a great challenge to image miRNAs with high accuracy in living cells. Here, we report a novel genetically encoded dual-color light-up RNA sensor for ratiometric imaging of miRNAs using Mango as an internal reference and SRB2 as the sensor module. This genetically encoded sensor is designed by expressing a splittable fusion of the internal reference and sensor module under a single promoter. This design strategy allows synchronous expression of the two modules with negligible interference. Live cell imaging studies reveal that the genetically encoded ratiometric RNA sensor responds specifically to mir-224. Moreover, the sensor-to-Mango fluorescence ratios are linearly correlated with the concentrations of mir-224, confirming their capability of determining mir-224 concentrations in living cells. Our genetically encoded light-up RNA sensor also enables ratiometric imaging of mir-224 in different cell lines. This strategy could provide a versatile approach for ratiometric imaging of intracellular RNAs, affording powerful tools for interrogating RNA functions and abundance in living cells.

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Synthesis of Tetrahydropyrazolo[4',3':5,6]pyrano[3,4- c ]quinolones by Domino Knoevenagel/Hetero Diels-Alder Reactions

An efficient Lewis acid mediated domino Knoevenagel/hetero Diels-Alder (DKHDA) reaction of pyrazolone derivatives with N -acrylated anthranilic aldehydes was developed, which afforded functionalized tetracyclic tetrahydropyrazolo[4',3':5,6]pyrano[3,4- c ]quinolones. The products were formed in good yields and with excellent regio- and stereoselectivity in favor of the cis-configured isomer.

Giant photoconductivity in NMQ[Ni(dmit)2]

The simple molecular salt NMQ[Ni(dmit)2] (NMQ = N-methylquinolinium, dmit = 1,3-dithiol-2-thione-4,5-dithiolate) functions as a diamagnetic insulator with an activation energy Ea(dark) of 0.20 eV. However, at 300 K, it exhibits ca. 40 times higher conductivity (σUV) under UV irradiation [(375±5) nm, 15.7 mWcm -2] than it does under dark conditions (σdark). The ratio σUV/σdark rapidly increases with decreasing temperature and reaches ca. 880 at 200 K. From the temperature dependence of σUV, the activation energy under irradiation Ea(UV) is 0.12 eV. These observations cannot be explained as the result of sample heating during UV irradiation. Rather, the X-ray photoelectron spectra of the sulfur and nickel atoms, the calculated band structure, and the UV/Vis spectra of the salt can all be explained consistently as follows: charge transfer between the Ni(dmit)2 moieties upon exposure to 375 nm UV light induces melting of the charge-ordered state and produces the unusually large photoconductivity of NMQ[Ni(dmit)2].

Screening of Minimalist Noncanonical Sites in Duplex DNA and RNA Reveals Context and Motif-Selective Binding by Fluorogenic Base Probes

We hypothesize that programmable hybridization to noncanonical nucleic acid motifs may be achieved by macromolecular display of binders to individual noncanonical pairs (NCPs). As each recognition element may individually have weak binding to an NCP, we d

Metal-free reduction of unsaturated carbonyls, quinones, and pyridinium salts with tetrahydroxydiboron/water

A series of unsaturated carbonyls, quinones, and pyridinium salts have been effectively reduced to the corresponding saturated carbonyls, dihydroxybenzenes, and hydropyridines in moderate to high yields with tetrahydroxydiboron/water as a mild, convenient, and metal-free reduction system. Deuterium-labeling experiments have revealed this protocol to be an exclusive transfer hydrogenation process from water. This journal is