Synthesis and biological activities of analogs of a lipid A biosynthetic precursor: 1-O-phosphono-oxyethyl-4'-O-phosphono-disaccharides with (R)-3-hydroxytetradecanoyl or tetradecanoyl groups at positions 2, 3, 2' and 3'

DOI: 10.1248/cpb.39.1994

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1994 - 1999 (1991)

Update date:2022-08-04

Topics:

Authors:

Kusama Kusama

Soga Soga

Ono Ono

Kumazawa

Shioya Shioya

Osada Osada

Kusumoto

Shiba Shiba

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Article abstract of DOI:10.1248/cpb.39.1994

Two novel analogs of a biosynthetic precursor of lipid A (2) were synthesized. The one analog (3) has acyl groups identical to those of 2, and the other (4) has tetradecanoyl groups in place of the (R)-3-hydroxytetradecanoyl groups of 2. Both 3 and 4 poss

Full text of DOI:10.1248/cpb.39.1994

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