Parallel synthesis of chiral pentaamines and pyrrolidine containing bis-heterocyclic libraries. Multiple scaffolds with multiple building blocks: A double diversity for the identification of new antitubercular compounds

DOI: 10.1016/j.bmcl.2009.07.010

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Bioorganic and Medicinal Chemistry Letters p. 5169 - 5175 (2009)

Update date:2022-08-05

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Authors:

Nefzi, Adel

Appel, Jon

Arutyunyan, Sergey

Houghten, Richard A.

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Article abstract of DOI:10.1016/j.bmcl.2009.07.010

Combinatorial chemistry offers a unique opportunity for the synthesis and screening of large numbers of compounds and significantly enhances the prospect of finding new drugs. Collaborative efforts with the Tuberculosis Antimicrobial Acquisition & Coordin

Full text of DOI:10.1016/j.bmcl.2009.07.010

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