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Synthesis and tripeptide amide derivatives and examination of their inhibitory effect on human leukocyte elastase (HLE)

DOI: 10.1248/cpb.36.3119

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 3119 - 3124 (1988)

Update date:2022-08-05

Topics: Synthesis Amide Mass spectrometry (MS) HPLC (high-performance liquid chromatography) Inhibitor Derivative Structure-Activity Relationship (SAR) Kinetic Analysis Enzyme assay Peptide bond Tripeptide Inhibitory effect Serine protease IC50 (Half-Maximal Inhibitory Concentration)

Authors:

Tsuda Tsuda

Teno Teno

Okada Okada

Nagamatsu

Okamoto Okamoto

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Article abstract of DOI:10.1248/cpb.36.3119

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Full text of DOI:10.1248/cpb.36.3119

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Product name:[(R)-1-(4-Acetyl-phenylcarbamoyl)-2-methyl-propyl]-carbamic acid benzyl ester

Cas No:118792-30-6

118792-30-6

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