Synthesis and properties of nucleoside derivatives acylated by chemically stable 2-(trimethylsilyl)benzoyl group

DOI: 10.1016/j.bmc.2009.07.003

Source and publish data:

Bioorganic and Medicinal Chemistry p. 5928 - 5932 (2009)

Update date:2022-08-04

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Authors:

Yamada, Ken

Taguchi, Haruhiko

Ohkubo, Akihiro

Seio, Kohji

Sekine, Mitsuo

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Article abstract of DOI:10.1016/j.bmc.2009.07.003

We report the synthesis and properties of nucleoside derivatives acylated by 2-(trimethylsilyl)benzoyl (TMSBz) that proved to be extremely stable under basic conditions when introduced into the 5′-hydroxyl group of thymidine, the 4-amino group of deoxycyt

Full text of DOI:10.1016/j.bmc.2009.07.003

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