Chemical synthesis and biological screening of 2-aminoimidazole-based bacterial and fungal antibiofilm agents

DOI: 10.1002/cbic.200900617

Source and publish data:

ChemBioChem p. 396 - 410 (2010)

Update date:2022-07-29

Topics:

Authors:

Rogers, Steven A.

Bero, Joseph D.

Melander, Christian

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Article abstract of DOI:10.1002/cbic.200900617

A collection of 2-aminoimidazole/triazole amides has been synthesized and screened for antibiofilm activity. This class of small molecules was found to modulate the biofilm activity of Pseudomonas aeruginosa, a multidrug-resistant strain of Acinetobacter

Full text of DOI:10.1002/cbic.200900617

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