183269-83-2 Usage
Synonyms
Rufinamide
Molecular weight
238.23 g/mol
Physical form
White to off-white crystalline powder
Solubility
Soluble in water
Medical use
Treatment of seizures associated with Lennox-Gastaut syndrome (a severe form of epilepsy)
Mechanism of action
Stabilizes neuronal membranes and modulates sodium channels, reducing excessive electrical activity in the brain
Administration
Typically administered orally
Common side effects
Dizziness, fatigue, nausea
Drug interactions
May interact with other medications
Safety guidance
Should be used under the guidance of a healthcare professional
Check Digit Verification of cas no
The CAS Registry Mumber 183269-83-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,3,2,6 and 9 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 183269-83:
(8*1)+(7*8)+(6*3)+(5*2)+(4*6)+(3*9)+(2*8)+(1*3)=162
162 % 10 = 2
So 183269-83-2 is a valid CAS Registry Number.
183269-83-2Relevant academic research and scientific papers
Bernotas, Ronald C.,Adams, Ginette
, p. 7339 - 7342 (1996)
A novel 1-benzylpiperazin-2-one nitrone has been synthesized. It readily undergoes [3 + 2] cycloadditions with alkynes and alkenes to give Δ4-isoxazolines and isoxazolidines, respectively, which can be reductively opened to 3-substituted piperazin-2-ones and 1,3-amino alcohols.
Bernotas, Ronald C.,Sing, Lily,Friedrich, Dirk
, p. 465 - 469 (2005)
The diastereoselectivity of the [2 + 3]-cycloaddition of 1-benzyl-2-piperazinone nitrone with several alkenes has been examined. exo-Type cycloadducts predominated for most substrates. Georg Thieme Verlag Stuttgart.
