Synthesis of 4-Substituted Prolines as Conformationally Constrained Amino Acid Analogues

DOI: 10.1021/jo00269a022

Source and publish data:

Journal of Organic Chemistry p. 1859 - 1866 (1989)

Update date:2022-08-04

Topics:

Authors:

Koskinen, Ari M. P.

Rapoport, Henry

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00269a022

Anionic substitution of N-(9-(9-phenylfluorenyl))-protected glutamic acid esters proceeds without loss of optical integrity to give 4-substituted glutamic acid derivatives.The 4-methyl, propyl, cyanomethyl, and phenyl analogues have thus been prepared.Pri

Full text of DOI:10.1021/jo00269a022

Products guided by the article

Product name:<2S,4(R,S)>-α-tert-butyl γ-methyl N-(9-(9-phenylfluorenyl))-4-iodoglutamate

Cas No:119595-80-1

R&D Labs maybe for 119595-80-1

Jiangsu Dacheng Pharmaceutical and Chemical Co.,Ltd

Contact:+86-0517-87036900

Address:Chuzhou Chemical park, Huai'an, Jiangsu Province
Shanghai shibo Chemical Co., Ltd

Contact:+86-021-60753516

Address:688 Qiushi Road, Jinshan High-tech Park, Shanghai, China,201512
Foreschem Co., Ltd

Contact:+86-533-3112891

Address:zibo
Zhuhai Rundu Pharmaceutical co.,Ltd

Contact:+86-756-7630755

Address:No.6,North Airport Road,Sanzao Town,Jinwan District
SINO Industries Company Limited(expird)

Contact:86-29-85369724

Address:No.111, Jiefang Road, Xi’an, China

Relevant to this article

Pd-catalyzed addition-carbocyclization of α,ω-diynes with H-P(O)R₂ compounds

Doi:10.1016/j.tetlet.2009.08.094
(2009)
Bioinspired Total Synthesis of the Dimeric Indole Alkaloid (+)-Haplophytine by Direct Coupling and Late-Stage Oxidative Rearrangement

Doi:10.1002/anie.201609285
(2016)
A New Copper^II/Isopropylidene-2,2-bis(oxazoline) catalyst and Its stable reactive complex with acryloyloxazolidinone in enantioselective reactions

Doi:10.1002/chem.200900908
(2009)
Synthesis and structure-activity relationships of dehydroaltenusin derivatives as selective DNA polymerase α inhibitors

Doi:10.1016/j.bmc.2009.08.051
(2009)
The synthesis of highly substituted Cyclooctatetraene scaffolds by metal-catalyzed [2+2+2+2] Cycloadditions: Studies on regioselectivity, dynamic properties, and metal chelation

Doi:10.1002/anie.200903859
(2009)
Synthesis of limonoid CDE fragments related to limonin and nimbinim

Doi:10.1016/j.tet.2010.07.020
(2010)

Article Doi