Synthesis of γ-butyrolactams by photoinduced PhSe group transfer radical cyclization and formal synthesis of (±)-isocynometrine with diphenyldiselenide as promoter

Article abstract of DOI:10.1021/jo9017099

(Chemical Equation Presented) We have developed a strategy for constructing nitrogen heterocycles by photoinduced PhSe group transfer radical cyclization. trans-α,β-Disubstituted γ-butyrolactams (2-pyrrolidinones) were prepared in good yields (38-73%) wit