Conjugate Addition of Grignard Reagents to Enones and Dienones

DOI: 10.1021/jo00271a014

Source and publish data:

Journal of Organic Chemistry p. 2317 - 2321 (1989)

Update date:2022-07-29

Topics:

Authors:

Modi, Sandeep P.

Gardner, John O.

Milowsky, Arnold

Wierzba, Mark

Forgione, Lisa

et al. et al.

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Article abstract of DOI:10.1021/jo00271a014

Grignard reaction with 16-dehydropregnenolone acetate, 1, results in 1,4-addition to the enone system.Introduction of even trace amounts of oxygen before the reaction has been fully quenched results in formation of 17α-hydroperoxides as well as the expect

Full text of DOI:10.1021/jo00271a014

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