Conjugate Addition of Grignard Reagents to Enones and Dienones

DOI: 10.1021/jo00271a014

Source and publish data:

Journal of Organic Chemistry p. 2317 - 2321 (1989)

Update date:2022-07-29

Topics:

Authors:

Modi, Sandeep P.

Gardner, John O.

Milowsky, Arnold

Wierzba, Mark

Forgione, Lisa

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00271a014

Grignard reaction with 16-dehydropregnenolone acetate, 1, results in 1,4-addition to the enone system.Introduction of even trace amounts of oxygen before the reaction has been fully quenched results in formation of 17α-hydroperoxides as well as the expect

Full text of DOI:10.1021/jo00271a014

Products guided by the article

Product name:3β-hydroxy-16α-phenylpregn-5-en-20-one

Cas No:119680-02-3

R&D Labs maybe for 119680-02-3

Shanghai birch chemical technology co.,ltd

Contact:+86-21-54096810

Address:No.2588,Jungong Road,Shanghai,China
Jinzhou Jiutai Pharmaceutical Co.,Ltd

Contact:+86-0416-5179890

Address:No.41, Taianli, Taihe District, Jinzhou, Liaoning
Jiaxing Anrui Material Technology Co., Ltd.

Contact:86-573-82651652 13305832579

Address:Room 407, Technology Building, 1369 Chennan Road, Jiaxing City, Zhejiang, China
Shandong Yuanli Science and Technology Co., Ltd.

Contact:86-0536-6777557

Address:Zhuliu Industiral Park,Changle County
Wuhan Hanye Chemical New Material Co.,Ltd

Contact:+86-27-85308141

Address:LiuDian, Panlongcheng Economic Development Zone, HuangPi district, Wuhan, Hubei 430311 P.R.China

Relevant to this article

Efficient, regioselective access to bicyclic imidazo[1,2-x]- heterocycles via gold- and base-promoted cyclization of 1-alkynylimidazoles

Doi:10.1021/jo902073m
(2009)
From serendipity to rational antituberculosis drug discovery of mefloquine-isoxazole carboxylic acid esters

Doi:10.1021/jm900340a
(2009)
SYNTHESIS OF 1H-PYRIDAZIN-4-ONE DERIVATIVES FROM ACETYLACETONE THROUGH ITS DIFLUOROBORYL CHELATE

Doi:10.1007/BF00962778
()
Stereoselective dehalogenation of (Z)-1-halo-1-alkenyldialkylborane with tributyltin hydride: The behavior of tributyltin hydride as a hydride donor

Doi:10.1016/S0040-4039(96)02324-6
(1997)
Model investigations of vanadium-protein interactions: Novel vanadium(III) and oxovanadium(IV) compounds with the diamidate ligand 1,2-bis(2-pyridinecarboxamide)benzene (H₂bpb)

Doi:10.1021/ic990837z
(2000)
Syntheses of morpholine-2,3-diones and 2-hydroxymorpholin-3-ones: Intermediates in the synthesis of aprepitant

Doi:10.1016/j.tetlet.2004.09.185
(2004)

Article Doi