Design and one-pot synthesis of α-aminophosphonates and bis(α-aminophosphonates) by iron(III) chloride and cytotoxic activity

DOI: 10.1016/j.ejmech.2009.07.009

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European Journal of Medicinal Chemistry p. 4266 - 4275 (2009)

Update date:2022-08-05

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Authors:

Rezaei, Zahra

Firouzabadi, Habib

Iranpoor, Nasser

Ghaderi, Abbas

Jafari, Mohammad Reza

Jafari, Abbas Ali

Zare, Hamid Reza

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Article abstract of DOI:10.1016/j.ejmech.2009.07.009

In this study, we used a solution of FeCl₃ in THF to facilitate the Mannich-type reaction of aldehyde, amine and phosphite compounds to form corresponding α-aminophosphonates in a one-pot, three-component reaction. Selected α-aminophosphonates

Full text of DOI:10.1016/j.ejmech.2009.07.009

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