Baker's yeast reduction of N-protected methyl 4-amino-3-oxobutanoates and 3-oxopentanoates

Article abstract of DOI:10.1055/s-1992-26123

Baker's yeast reduction of N-tert-butoxycarbonyl (Boc) or N-benzyloxycarbonyl (Cbz) protected methyl 4-amino-3-oxopentanoates 4b-e and 4-amino-3-oxobutanoates 7a,b stereoselectively afforded the erythro-hydroxy esters 5b-e and (R)-hydroxy esters 8a,b, res