
Tetrahedron p. 4221 - 4232 (1988)
Update date:2022-08-05
Topics:
Gennari, Cesare
Schimperna, Giuliana
Venturini, Isabella
TiCl4 mediated addition of silyl ketene acetals derived from N-methylephedrine esters to various aldehydes and imines was used as the key-step in the enantio- and diastereo-controlled synthesis of β-lactams.Thus 3,4-trans and cis substituted-2-azetidinone
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