Palladium-Catalyzed Carbonylation of Allylamines. Synthesis of β,γ-Unsaturated Amides by One-Carbon Homologation of Allylamines

Article abstract of DOI:10.1016/S0040-4020(01)80767-5

Palladium-catalyzed carbonylation of allylamines under CO (50 atm) at 110 deg C proceeds highly efficiently to give the correponding β,γ-unsaturated amides.The carbonylation occurs at the less substituted carbon of allyl units to give linear amides with h