Hydroxy Group as a Regio- and Stereochemical Control Element for Sequential Metal-Catalyzed and Thermal Cyclizations

DOI: 10.1021/jo00271a006

Source and publish data:

Journal of Organic Chemistry p. 2271 - 2274 (1989)

Update date:2022-09-26

Topics:

Authors:

Trost, Barry M.

Lee, Donna C.

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Article abstract of DOI:10.1021/jo00271a006

Stereocontrolled creation of fused ring systems from acyclic precursors in vokes the powerful directive effect of the hydroxy group in which regioselectivity of a metal-catalyzed reaction totally changes and diastereofacial selectivity of the thermal step shows an unusual dependance on dienophile.

Full text of DOI:10.1021/jo00271a006

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