
European Journal of Organic Chemistry p. 6367 - 6378 (2009)
Update date:2022-08-04
Topics:
Ullrich, Angelika
Herrmann, Jennifer
Mueller, Rolf
Kazmaier, Uli
Pretubulysin, a biosynthetic precursor of the tubulysins, shows potent biological activity in the subnanomolar range towards various tumor cell lines. Its activity is only slightly less than those of the structurally more complex tubulysins. With a straig
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