AN EFFICIENT SYNTHESIS OF 5-ARYL(or ALKYL)AMINO-4-ETHOXYCARBONYL-2-METHYLTHIO-1,3-THIAZOLES FROM DIMETHYL N-(ETHOXYCARBONYLMETHYL)IMINODITHIOCARBONATE AND ISOTHIOCYANATES.

DOI: 10.3987/COM-88-4613

Source and publish data:

Heterocycles p. 2177 - 2184 (1988)

Update date:2022-09-26

Topics:

Authors:

Alvarez-Ibarra, Carlos

Gil, Matilde

Ortiz, Paloma

Quiroga, Maria L.

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Article abstract of DOI:10.3987/COM-88-4613

An efficient synthesis of perfunctionalyzed 1,3-thiazoles 2a-2b with good yields has been carried out by a cyclocondensation reaction between the α-metallated dimethyl N-(ethoxycarbonylmethyl)iminodithiocarbonate and aryl or alkylisothiocyanates.

Full text of DOI:10.3987/COM-88-4613

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