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Microwave assisted synthesis of some 2, 4 dihydroxy 1, 8-naphthyridines and their derivatives devoid of solvent and catalyst

DOI: 10.1515/HC.2009.15.1.35

Source and publish data:

Heterocyclic Communications p. 35 - 41 (2009)

Update date:2022-08-04

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Authors:

Maringanti, Thirumala CharyMaringanti, Thirumala Chary

Eppakayala, LaxminarayanaEppakayala, Laxminarayana

Sripelly, Shiva ShankarSripelly, Shiva Shankar

Atmakuri, NarenderAtmakuri, Narender

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Article abstract of DOI:10.1515/HC.2009.15.1.35

Reaction of substituted 2-aminopyridines with diethylmalonates yields 2, 4- dihydroxy-l, 8-Naphthyridenes(l-18). The 6-chloro-2, 4-dihydroxy-l, 8- naphthyridene (5) when treated with different reagents varied substituted derivatives are produced. 6- chloro-2, 4-dihydroxy-l, 8-naphthyridene(5) when treated with sodium azide offered 2, 4-dihydroxy-1, 8-naphthyridene-6-thiones (19-21). 6-azido-1, 8-naphthyridine-2, 4- diols(22-24) were obtained by reacting 5 with sodiumazide. The 6-hydrazinyl-l, 8-naphthyridine-2, 4-diols (25-27) and 2, 4, 6-trihydroxy-l, 8-naphthyridenes (28-30) were produced by the reaction of 5 with hydrazine hydrate and acetic acid respectively.

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Full text of DOI:10.1515/HC.2009.15.1.35

Brought to you by | National Chung Hsing University  
Authenticated | 140.120.135.222  
Download Date | 3/28/14 8:13 AM  
Brought to you by | National Chung Hsing University  
Authenticated | 140.120.135.222  
Download Date | 3/28/14 8:13 AM  
Brought to you by | National Chung Hsing University  
Authenticated | 140.120.135.222  
Download Date | 3/28/14 8:13 AM  
Brought to you by | National Chung Hsing University  
Authenticated | 140.120.135.222  
Download Date | 3/28/14 8:13 AM  
Brought to you by | National Chung Hsing University  
Authenticated | 140.120.135.222  
Download Date | 3/28/14 8:13 AM  
Brought to you by | National Chung Hsing University  
Authenticated | 140.120.135.222  
Download Date | 3/28/14 8:13 AM  
Brought to you by | National Chung Hsing University  
Authenticated | 140.120.135.222  
Download Date | 3/28/14 8:13 AM  
Brought to you by | National Chung Hsing University  
Authenticated | 140.120.135.222  
Download Date | 3/28/14 8:13 AM  

Products guided by the article

Product name:3-benzyl-6-mercapto-1,8-naphthyridine-2,4-diol

Cas No:1209781-83-8

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