First Observation of a Helical Peptide Containing a Chiral Residue without a Preferred Screw Sense

Article abstract of DOI:10.1021/ja00199a051

The molecular and crystal structure of the fully blocked, chiral pentapeptide Ac-(Aib)2-S-Iva-(Aib)2-OMe was determined by X-ray diffraction.It was found that the two crystallographically independent molecules (A and B), aligned in an antiparallel arrange