Trityl Salt Catalyzed Aldol Reaction between α,β-Acetylenic Ketones and Silyl Enol Ethers

Article abstract of DOI:10.1246/cl.1988.1491

In the presence of a catalytic amount of trityl salt, α,β-acetylenic ketones react with silyl enol ethers to afford the corresponding aldol adducts (1,2-addition products) stereoselectively in high yields.Naturally occurring monoterpenes, trans- and cis-tagetones, are synthesized by the use of this reaction.