Synthesis and Biological Activity of 9,11-Dehydrovitamin D3 analogues: Stereoselctive Preparation of 6β-Vitamin D Vinylallenes and a Concise Enynol Synthesis for Preparing the A-Ring

DOI: 10.1021/jo00278a018

Source and publish data:

Journal of Organic Chemistry p. 4072 - 4083 (1989)

Update date:2022-08-05

Topics:

Authors:

Okamura, William H.

Aurrecoechea, J. Miguel

Gibbs, Richard A.

Norman, Anthony W.

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Article abstract of DOI:10.1021/jo00278a018

The Δ⁹⁽¹¹⁾-unsaturated vitamin D analogues 5a and 5b are of biochemical interest because they are incapable of tautomerizing via a <1,7>sigmatropic hydrogen shift to a previtamin structure related to 3 and also becouse they possess a perturbed

Full text of DOI:10.1021/jo00278a018

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