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Product FOB Price Min.Order Supply Ability Supplier
High purity 99% xanthophyll from alfalfa
Cas No: 127-40-2
USD $ 1.0-10.0 / Kilogram 1 Kilogram 1000 Kilogram/Month Kono Chem Co.,Ltd Contact Supplier
High quality of Xanthophyll
Cas No: 127-40-2
USD $ 1.0-1.0 / Metric Ton 1 Metric Ton 1000 Kilogram/Month Career Henan Chemical Co Contact Supplier
Xanthophyll
Cas No: 127-40-2
No Data 1 Gram No Data CHANGZHOU HANGYU PHARMACEUTICAL TECHNOLOGY CO., LTD Contact Supplier
Marigold Extract lutein
Cas No: 127-40-2
USD $ 60.0-60.0 / Kilogram 1 Kilogram 300 Kilogram/Month Greenutra Resource Inc Contact Supplier
GMP High Purity marigold extract Lutein and Zeaxanthin Powder UV/HPLC 5%-90%
Cas No: 127-40-2
USD $ 1.0-1.0 / Kilogram 1 Kilogram 100000 Kilogram/Month Wuhan Recedar Biotechnology Co., Ltd Contact Supplier
Xanthophyll
Cas No: 127-40-2
No Data No Data No Data Cartoon Ingredients Co., Ltd Contact Supplier
Xanthophyll Manufacturer/High quality/Best price/In stock
Cas No: 127-40-2
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Hangzhou Dayangchem Co., Ltd. Contact Supplier
High purity 99% lutein
Cas No: 127-40-2
USD $ 1.0-3.0 / Metric Ton 1 Metric Ton 10 Metric Ton/Day Hebei yanxi chemical co.,LTD. Contact Supplier
High quality Lutein Xanthophyll CAS:127-40-2
Cas No: 127-40-2
No Data 1 Metric Ton 25 Metric Ton/Week Hefei TNJ chemical industry co.,ltd Contact Supplier
Lutein CAS 127-40-2 In stock
Cas No: 127-40-2
USD $ 1.0-1.0 / Metric Ton 1 Metric Ton 5 Metric Ton/Day Chemwill Asia Co., Ltd. Contact Supplier

127-40-2 Usage

Who needs Xanthophyll supplements?

1. People who use computer for long time
2. People with dry eye syndrome
3. People whose eyes are easily fatigue with tears
4. People with retinal degeneration that caused by degradation of renal function
5. People with high myopia
6. People with degenerative macular area lesions
7. People who received Laser Surgery
8. People with diabetic retinopathy

Which food is Xanthophyll rich?

Xanthophyll is rich in some green vegetables and fruits such as cabbage, spinach, lettuce, green beans and rapes, but chlorophyll, β-carotene and other epoxy carotenoids and oxygen substituted derivatives of carotenoids are also rich in such plants, making is not easy to extract the pure xanthophyll. After long-term searching, people found very high levels of Xanthophyll and zeaxanthin and less impurities of other carotenoids in flowers of marigold, which makes separation and purification easy, thus marigold can be a good source for industrial production of Xanthophyll. In addition, this product and zeaxanthin are also rich in some yellow-orange fruits such as mango, papaya, peaches, and pumpkins.
The above information is edited by the Chemicalbook of Cheng Jingmin.

Uses

One of the most widespread carotenoid alcohols in nature. Originally isolated from egg yolk, also isolated by chromatography from nettles, algae, and petals of many yellow flowers.

Carotenoids

Xanthophyll is a type of carotenoid, which belongs to photosynthetic pigments and naturally widely presents in vegetables (such as spinach, kale, broccoli, etc.), flowers, fruits and other plants. It can absorb and transfer light energy to Chlorophyll a at a particular state to convert light energy. It plays a role in protecting chlorophyll.
Pure Xanthophyll is a rhombus yellow crystal with metallic luster, and it is unstable when exposed to light and hydrogen, insoluble in water and easily soluble in grease and fatty solvents. It shall be stored in a cool dry place, away from light and air.
Xanthophyll is the most important nutritive component in human retina. There is a high concentration of Xanthophyll in macula (central vision) and lens of the eye retina. The human body cannot synthesize Xanthophyll itself, and it must be taken up from food. After breaking through all difficulties, Xanthophyll goes into the lens and macular to perform antioxidant effects, and neutralize harmful free radicals, and filter out the blue light (which is harmful to the eye), and avoid oxidation damage to eyes caused by sunlight.
Natural Xanthophyll is an excellent antioxidant, which can prevent cell senescence and body organs aging when added to food with an appropriate amount. It can also prevent eyesight degeneration and blindness that caused by age-related retina macular degeneration, and can also be used as feed additives for staining of poultry meat and eggs, as well as a colorant and dietary supplements in food industry.
Carotenoids are the generic terms of an important kind of natural pigments, belonging to compounds. The yellow, orange or red pigments that commonly found in animals, higher plants, fungi, algae and bacteria are mainly β-carotene and a-carotene, hence the name. Since carotene was isolated in the early 19th century, there are more than 600 known carotenoids in nature, of which only about 20 kinds present in the human blood and tissues. Carotenoids that found in human body include d-carotene, P-carotene, cryptoxanthin, xanthophyll, lycopene and zeaxanthin, and they are insoluble in water and soluble in fats and fatty solvents.

Identification test

Xanthophyll is not dissolve in water, but soluble in hexane.
Spectroscopy: The chloroform solution has the maximum absorption at about 445nm.
Chloroform solution turns to blue coloration when adding an excess of Cart-Price test solution.
Toxicity: not limited by ADII yet (FAO/WHO, 2001).

Function

Protection of eyesight
Xanthophyll plays an important role in protecting the macula of the retina. The absence of Xanthophyll can easily cause macular degeneration and blurred vision, and with the further symptoms of vision degeneration, myopia and so on. Xanthophyll is a precursor of NA, and it can be transformed into VA in the human body. The main physiological function for eyes of Xanthophyll is as antioxidants and light protectors. Optic nerves are non-renewable and highly vulnerable to harmful free radicals, and the antioxidant effects of Xanthophyll can inhibit the formation of harmful free radicals. Xanthophyll can absorb a large number of blue visible lights, which have the close wavelengths to ultraviolet lights and are a kind of harmful lights that can reach the retina and with the largest potential hazardous. Before reaching the sensitive cells of the retina, the light goes through the most heavily gathering area of Xanthophyll. If Xanthophyll is rich now, the damage can be lower to the minimum.
Reducing the incidence of cataract
Cataract is the major eye disease causing of blindness in the world. Recent studies showed that by increasing the intake of Xanthophyll, the incidence of cataracts can can be reduced. So far, the mechanism is that the lower density of macular pigment is closely related to the higher lens visual density in the elders, and the higher the lens visual density is considered to be a obvious feature of cataract.
The antioxidant effect
Xanthophyll has strong antioxidant effect, and it can inhibit the activity of reactive oxygen species and prevent its damage to normal cells. Related experiments showed that reactive oxygen species could react with DNA, proteins, lipids, and weaken their physiological functions, and thus cause diseases such as cancer, atherosclerosis, and age-related macular degenerative disorders. Xanthophyll can quench singlet oxygen physically or chemically, thereby protecting the body from injury and enhancing the body's immunity.
Retarding atherosclerosis
Recent research results showed that Xanthophyll has a retarding effect on early process of atherosclerosis. The main reason is the relationship between the intimal thickness of the main artery blood vessels and the content of Xanthophyll in blood. Low content of Xanthophyll in blood can easily cause thickening of arterial walls. With the increasing content of Xanthophyll, the trend of arterial wall thickening decreases significantly. Meanwhile, the Xanthophyll in arterial wall cells can reduce oxidation of LDL cholesterol.
Anticancer effects
Several studies have shown that Xanthophyll can inhibit a variety of cancers, such as breast cancer, prostate cancer, colorectal cancer, and skin cancer. According to a recent pharmaceutical research of New York University School, there is a very close relationship between reducing the incidence of breast cancer and the amount of Xanthophyll intake, and the survey found that the incidence of breast cancer in the group with a low intake of Xanthophyll was (2.08-2.21) times higher than the group with a high intake of Xanthophyll. This effect role may be related to indirect immunomodulatory of synergy with other organs and tissues. The study concluded that dietary intake of Xanthophyll can inhibit neoplasms and may even play a role in cancer prevention. It is recommended daily intake of 400 g~600 g fruits and vegetables per capita can make reduce the relative risk of cancer by 50%.

Production methods

Xanthophyll is derived from the extraction of pasture or alfalfa, in which chlorophyll was removed through saponification. and then Xanthophyll was purified with a solvent and then desolventized. The solvent used is methanol, ethanol, isopropanol, hexane, acetone, methylene chloride and methyl ethyl ketone, according to the specified rules of FAO/WHO (1997).
InChI:InChI=1/C40H56O2/c1-29(17-13-19-31(3)21-23-37-33(5)25-35(41)27-39(37,7)8)15-11-12-16-30(2)18-14-20-32(4)22-24-38-34(6)26-36(42)28-40(38,9)10/h11-25,35-37,41-42H,26-28H2,1-10H3/b12-11+,17-13+,18-14+,23-21+,24-22+,29-15+,30-16+,31-19+,32-20+/t35?,36-,37+/m1/s1

127-40-2 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
Sigma-Aldrich (79766)  Lutein solution  1 mg/L in ethanol, analytical standard 127-40-2 79766-2.5ML 5,984.55CNY Detail
Sigma-Aldrich (07168)  Lutein  analytical standard 127-40-2 07168-5MG 24,710.40CNY Detail
Sigma-Aldrich (07168)  Lutein  analytical standard 127-40-2 07168-1MG 5,434.65CNY Detail

127-40-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name lutein

1.2 Other means of identification

Product number -
Other names Xanthophyll

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:127-40-2 SDS

127-40-2Related news

Xanthophyll (cas 127-40-2) content of selected vegetables commonly consumed in the Philippines and the effect of boiling09/30/2019

The purpose of this study was to quantify xanthophylls in selected vegetables commonly consumed in the Philippines and to investigate the effect of boiling on their availability. Thirteen vegetables were grouped into green-leafy and non-leafy. Results showed that fresh malunggay contains the hig...detailed

An efficient one-step scheme for the purification of major Xanthophyll (cas 127-40-2) carotenoids from lettuce, and assessment of their comparative anticancer potential09/29/2019

The foremost problem in carotenoid research is the excessive cost and difficulty of maintaining pure carotenoid compounds. This work presents an economical, efficient, and simplified one-step scheme for the purification of four major xanthophyll carotenoids from lettuce by utilizing preparative ...detailed

Photoprotective role of the Xanthophyll (cas 127-40-2) cycle studied by means of modeling of Xanthophyll (cas 127-40-2)–LHCII interactions09/28/2019

The problem of photoprotection associated with the xanthophyll cycle is addressed by examination of effects of exogenous violaxanthin and zeaxanthin on isolated antenna complex LHCII. Analysis of electronic absorption spectra suggests multiple sites of binding of violaxanthin and zeaxanthin to t...detailed

Preparation of microencapsulated Xanthophyll (cas 127-40-2) for improving solubility and stability by nanoencapsulation10/01/2019

A microencapsulated xanthophyll preparation method, using an ultrasonic cell grinder synchronizing emulsification inclusion procedure, was developed for improving the stability and water solubility of xanthophyll. The microencapsulated xanthophyll was analyzed, tested and characterized by method...detailed

Extending Fluspect to simulate Xanthophyll (cas 127-40-2) driven leaf reflectance dynamics09/25/2019

The xanthophyll cycle regulates the energy flow to photosynthetic reaction centres of plant leaves. Changes in the de-epoxidation state (DEPS) of xanthophyll cycle pigments can be observed as changes in the leaf absorption of light with wavelengths between 500 to 570 nm. These spectral changes c...detailed

The peculiar NPQ regulation in the stramenopile Phaeomonas sp. challenges the Xanthophyll (cas 127-40-2) cycle dogma09/10/2019

In changing light conditions, photosynthetic organisms develop different strategies to maintain a fine balance between light harvesting, photochemistry, and photoprotection. One of the most widespread photoprotective mechanisms consists in the dissipation of excess light energy in the form of he...detailed

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